What is an NMN Supplement?
What is an NMN Supplement?
NMN (Nicotinamide Mononucleotide) is a popular ‘longevity supplement that has gained mainstream attention in recent years. It is a compound naturally derived from vitamin B3 and plays a key role in the body’s ability to produce NAD+ (Nicotinamide Adenine Dinucleotide).
NAD+ is an essential enzyme found in every cell of the body, supporting vital biological processes that contribute to overall health. Research has explored its potential anti-aging and life extending benefits, particularly in animal studies, highlighting its role in energy production, DNA repair, and cellular function.
As interest in longevity and wellness grows, NMN is becoming a sought after supplement for those looking to support healthy ageing and overall vitality.
NMN Supplement Benefits – Hype or Science?
The claimed benefits of NMN supplements include:
Increased energy throughout the day without crashes
Improved sleep quality, leading to better rest and recovery
Enhanced mental clarity and concentration, boosting productivity
Elevated metabolism, potentially reducing age-related weight gain
While these claims sound promising, how much of this is actually backed by science?
Currently, most studies on NMN have been conducted on animals. Research has shown improvements in:
Insulin sensitivity
Cardiac health
Cognitive function
Reduced age-related decline
Further Studies:
For NMN to be considered truly effective, more research is needed on healthy individuals taking the supplement without changing their long-term diet or lifestyle. Despite claims of metabolic benefits, current studies have found no significant improvements in key health markers such as:
Blood glucose (HbA1c)
Cholesterol levels
Blood pressure
Body composition
However, some promising findings do exist. One study on prediabetic menopausal women found that taking 250mg of NMN per day improved insulin sensitivity. Another study suggested that muscle NAD+ levels in older adults were similar to those of younger individuals when they followed a healthy diet and exercised regularly.
REFERENCES:
Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women - https://pmc.ncbi.nlm.nih.gov/articles/PMC8550608/
Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men - https://pubmed.ncbi.nlm.nih.gov/31685720/
Healthy ageing and muscle function are positively associated with NAD+ abundance in humans - https://pubmed.ncbi.nlm.nih.gov/37118369/
A Food-First Approach
Before turning to supplements, it’s important to note that NMN is naturally present in foods like cow’s milk, beef, prawns, and vegetables such as broccoli, edamame, cucumber, avocado, and tomato when cooked at low temperatures. As a Nutritional therapist, I will always recommend a wholefood approach to a balanced diet as the best way to support health and longevity.
While NMN supplements may hold promise, the science is still evolving, and a well-rounded diet should always be the foundation of good health.
NMN is not a Replacement for Healthy Living
While NMN supplements may offer potential benefits, the fundamentals of healthy ageing, including a nutrient-dense diet, regular exercise, quality sleep, and stress management, remain the most reliable way to support long-term health.
If you are considering NMN, think of it as a possible addition to a well-rounded lifestyle, rather than a substitute for healthy habits.
